New hope for kidney disease: early combo therapy may slow IgA nephropathy

NCT ID NCT03188887

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding early steroids or SGLT2 inhibitors to standard blood pressure medication can better protect kidney function in people with IgA nephropathy who have severe kidney damage. 62 adults with active disease were randomly assigned to receive either the combination therapy or standard care alone. The goal was to see if the extra treatment could prevent worsening kidney function over two years.

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Conditions

The condition(s) this trial relates to.

IgA glomerulonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker Enfants-malades

    Paris, Paris, 75015, France