New combo therapy shows promise against rare skin cancer
NCT ID NCT06947928
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 21 times
Summary
This study tests whether adding an experimental drug (IFx-Hu2.0) to a standard immunotherapy (pembrolizumab) can shrink tumors better than placebo plus pembrolizumab in people with advanced or metastatic Merkel cell carcinoma. About 118 adults with this rare skin cancer will receive injections directly into a tumor. The goal is to control the disease, not cure it.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED OR METASTATIC MERKEL CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Atlantic Health System
RECRUITINGMorristown, New Jersey, 07960, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
East Carolina University
RECRUITINGGreenville, North Carolina, 27834, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Fred Hutchinson Cancer Research Center
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Inova Schar Cancer
RECRUITINGFairfax, Virginia, 22031, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Mayo Clinic Comprehensive Cancer Center
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-••••
Contact
-
Mayo Clinic Comprehensive Cancer Center
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Stanford Health Care - Skin Cancer Program
RECRUITINGStanford, California, 94304, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Sylvester Comprehensive Cancer Center
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77384, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
USC Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
Contact
-
University of California San Francisco - Helen Diller Family Comprehensive Cancer Center
RECRUITINGSan Francisco, California, 94143, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Colorado Hospital - Anschutz Cancer Pavilion
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
West Virginia University
RECRUITINGMorgantown, West Virginia, 26506, United States
Contact
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.