New pill could slow deadly lung scarring – early trial underway
NCT ID NCT05571059
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether an oral drug called ifetroban can slow the decline in lung function for people with idiopathic pulmonary fibrosis (IPF), a progressive lung-scarring disease. About 128 adults aged 40 and older with IPF will receive either ifetroban or a placebo daily for 52 weeks. The main goal is to see if ifetroban reduces the drop in forced vital capacity (a measure of lung volume) compared to placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ifetroban
What this could lead to
If it works, this could point toward a new oral treatment to slow lung function decline in people with idiopathic pulmonary fibrosis.
What could go wrong
This is an early Phase 2 trial with only 128 participants, so results may not confirm benefit. The drug may not slow disease progression or could cause side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Avera Research Institute
RECRUITINGSioux Falls, South Dakota, 57108, United States
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Baylor University Medical Center
RECRUITINGDallas, Texas, 75246, United States
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Beaumont Hospital, Royal Oak
RECRUITINGRoyal Oak, Michigan, 48073, United States
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Bend Memorial Hospital
RECRUITINGBend, Oregon, 97701, United States
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Biosolutions Clinical Research
RECRUITINGLa Mesa, California, 91942, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Indiana University Health
RECRUITINGIndianapolis, Indiana, 46202, United States
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Mayo Clinic Jacksonville
RECRUITINGJacksonville, Florida, 32224, United States
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Miami VA Health System
RECRUITINGMiami, Florida, 33125, United States
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Northwestern Medicine
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Premier Pulmonary Critical Care and Sleep Medicine
RECRUITINGDenison, Texas, 75020, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pulmonary & Sleep Specialists
RECRUITINGDickson, Tennessee, 37055, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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UNC Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UW Health University Hospital
RECRUITINGMadison, Wisconsin, 53792, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••