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New drug shows promise for Hard-to-Treat cancers with specific gene flaw

NCT ID NCT04174716

Completed Disease control Sponsor: Idience Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called IDX-1197 in 108 adults with solid tumors that have a specific gene change (HRR mutation) and who had no other good treatment options. The goal was to find the safest dose and see if the drug could shrink tumors. The trial was completed, but results are not yet public.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HOMOLOGOUS RECOMBINATION DEFICIENCY HOMOLOGOUS RECOMBINATION REPAIR GENE MUTATION SOLID TUMORS

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499, South Korea

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Cha University Bundang Medical Center

    Seongnam-si, 13496, South Korea

  • Chonnam National University Hwasun Hospital

    Hwasun, Jeollanam-do, 58128, South Korea

  • Dong-a University Hospital

    Busan, 49201, South Korea

  • Gachon University Gil Medical Center

    Incheon, 21565, South Korea

  • Gyeongsang National University Hospital

    Jinju, Gyeongsangnam-do, 52727, South Korea

  • Inje University Haeundae Hospital

    Busan, 48108, South Korea

  • Kangbuk Samsung Hospital

    Seoul, 03181, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Korea University Guro Hospital

    Seoul, 08308, South Korea

  • National Cancer Centre

    Goyang, Gyeongggi-do, 10408, South Korea

  • Pusan National University Yangsan Hospital

    Busan, 50612, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul Metropolitan Government Seoul National University Boramae Medical Center

    Seoul, 07061, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    Seoul, 06591, South Korea

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