New drug combo shows promise in early stomach cancer trial

NCT ID NCT04725994

Ongoing Disease control Sponsor: Idience Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new drug called IDX-1197 combined with standard chemotherapy (XELOX or irinotecan) in 87 people with advanced stomach cancer. The main goal is to find the safest dose and check for side effects. It is not yet known if the combination works better than current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: IDX-1197 (a drug) combined with chemotherapy (capecitabine, oxaliplatin, or irinotecan)
What this could lead to: If it works, this could point toward a new treatment option for advanced gastric cancer that may help control the disease.
What could go wrong: This is an early-phase trial with only 87 patients, so it is too small to prove effectiveness. The drug may cause side effects or fail to improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastric cancer gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRIC CANCER

Contacts and locations

Locations

Asan Medical Center

Seoul, South Korea
Astera Cancer Care

East Brunswick, New Jersey, 08816, United States
Beijing Cancer Hospital

Beijing, China
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Dana Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Dong-A University Hospital

Busan, 49201, South Korea
Hematology Oncology Clinic Baton Rouge / Sarah Cannon

Baton Rouge, Louisiana, 70809, United States
Jeonbuk National University Hospital

Jeonju, Jeollabuk-do, South Korea
Korea University Anam Hospital

Seoul, 02841, South Korea
Korea University Guro Hospital

Seoul, 08308, South Korea
Samsung Medical Center

Seoul, South Korea
Seoul National University Bundang Hospital

Seongnam, South Korea
Seoul National University Hospital

Seoul, South Korea
Severance Hospital - Yonsei Cancer Center

Seoul, South Korea
Shanghai East Hospital

Shanghai, China
The Sixth Affiliated Hospital of Sun Yat-Sen University

Guangzhou, China
USC Norris Comp. Cancer Ctr Hospital

Los Angeles, California, 90033, United States

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