New pill could stop the maddening itch of prurigo nodularis

NCT ID NCT07236099

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests an experimental drug called ICP-332 for people with prurigo nodularis, a skin condition causing many intensely itchy bumps. About 135 adults will receive either the drug or a placebo to see if it reduces itching and clears the bumps over 16 weeks. The goal is to find a safe, effective dose to ease this chronic itch.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AKK MEDlCAL Spółka z ograniczoną Odpowiedzialnością, Centrum Medyczne Tu się Leczy

    RECRUITING

    Gdansk, 80-280, Poland

  • Affiliated Hangzhou First People's Hospital,School of Medicine ,Westlake University

    RECRUITING

    Hangzhou, Zhejiang, 250022, China

  • Amicare Centrum Medyczne

    RECRUITING

    Lodz, 91-495, Poland

  • Apex Clinical Research Center

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Cahaba Dermatology and Skin Health Center

    RECRUITING

    Birmingham, Alabama, 35244, United States

  • Centrum Badawcze Panaceum

    RECRUITING

    Malbork, 82-200, Poland

  • Chengdu Second People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610021, China

  • Cordova Research Institute

    RECRUITING

    Sweetwater, Florida, 33182, United States

  • Dawes Fretzin Clinical Research Group LLC

    RECRUITING

    Indianapolis, Indiana, 46250, United States

  • Dermatologischen Gemeinschaftspraxis Dres. Quist

    RECRUITING

    Mainz, 55128, Germany

  • Dermatology Hospital of Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510091, China

  • Driven Research, LLC

    RECRUITING

    Coral Gables, Florida, 33134, United States

  • Jingzhou Central Hospital

    RECRUITING

    Jingzhou, Hubei, 434020, China

  • Medical Dermatology Specialists

    RECRUITING

    Phoenix, Arizona, 85006, United States

  • Minnesota Clinical Study Center

    RECRUITING

    New Brighton, Minnesota, 55112, United States

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

  • Revival Research Institute, LLC

    RECRUITING

    Troy, Michigan, 48084, United States

  • Rosenpark Research

    RECRUITING

    Darmstadt, 64283, Germany

  • Shandong Provincial Dermatology Hospital

    RECRUITING

    Jinan, Shandong, 250022, China

  • Shenyang Seventh People's Hospital

    RECRUITING

    Shenyang, Liaoning, 110003, China

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610072, China

  • Skin Specialists, PC

    RECRUITING

    Omaha, Nebraska, 68144, United States

  • The Derm Institute of West Michigan

    RECRUITING

    Caledonia, Michigan, 49316, United States

  • The First Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, 400016, China

  • The First Affiliated Hospital of Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, 350005, China

  • The First Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, 050000, China

  • The Second Affiliated Hospital of Wannan Medical College

    RECRUITING

    Wuhu, Anhui, 241000, China

  • The first hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130021, China

  • Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300131, China

  • Twoja Przychodnia

    RECRUITING

    Nowa Sól, 67-100, Poland

  • Twoja Przychodnia Centrum Medyczne

    RECRUITING

    Poznan, 60-324, Poland

  • Uni Berlin Chartie Derma

    RECRUITING

    Berlin, 12203, Germany

  • Uni Leipzig Derma

    RECRUITING

    Leipzig, 04103, Germany

  • Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, 410008, China

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Other studies related to the condition(s) this trial covers.