Ibuprofen may tame high PSA, study hopes to cut unnecessary biopsies

NCT ID NCT05512754

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the common anti-inflammatory drug ibuprofen can reduce elevated PSA levels in men. High PSA often leads to prostate biopsies, but inflammation can falsely raise PSA. The trial enrolls 200 men with PSA over 3 ng/mL and no known prostate cancer. Participants take ibuprofen or a placebo, and researchers measure PSA changes and urinary symptoms over time.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albany Medical College

    RECRUITING

    Albany, New York, 12208, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • The Pennsylvania State University at The Milton S. Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact