New hope for ALS patients: experimental drug aims to preserve muscle function

NCT ID NCT04057898

Summary

This clinical trial is testing whether an experimental drug called MN-166 (ibudilast) can slow the progression of ALS (amyotrophic lateral sclerosis or Lou Gehrig's disease). The study involves 234 adults recently diagnosed with ALS, who will take either the drug or a placebo for 12 months to see if it helps maintain their physical abilities and strength. The main goal is to see if the drug can slow the decline in daily function and potentially extend survival time for people living with this condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Augusta University

    Augusta, Georgia, 30912, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Hennepin Healthcare Research Institute

    Minneapolis, Minnesota, 55415, United States

  • Hopital de L'Enfant-Jesus, CHU de Quebec-Universite Laval

    Québec, G1J 1Z4, Canada

  • Indiana University IU Health Neuroscience Center

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Lehigh Valley Health Network

    Allentown, Pennsylvania, 18103, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • McMaster University Medical Center

    Hamilton, Ontario, L8N 3Z5, Canada

  • Montreal Neurological Institute and Hospital

    Montreal, Quebec, H3A 2B4, Canada

  • SUNY Upstate Medical University

    Syracuse, New York, 13210, United States

  • Sunnybrook Research Institute

    Toronto, Ontario, M4N 3M5, Canada

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2G3, Canada

  • University of California

    Orange, California, 92868, United States

  • University of Saskatchewan - Sastakoon Hospital

    Saskatoon, Saskatchwean, S7K 0M7, Canada

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.