New combo tackles tough myeloma in early trial

NCT ID NCT03702725

First seen Jan 10, 2026 · Last updated May 19, 2026 · Updated 15 times

Summary

This early-phase study tested a three-drug combination (ibrutinib, lenalidomide, and dexamethasone) in 14 people whose multiple myeloma had returned or stopped responding to treatment. The main goal was to find safe doses and identify side effects. While the approach aims to control the disease, it is not a cure, and ongoing treatment is typically needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • The Ohio State University Wexner Medical Center/James Cancer Hospital

    Columbus, Ohio, 43210, United States

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.