New drug combo shows promise against rare blood cancer

NCT ID NCT04273139

First seen May 15, 2026 · Last updated May 18, 2026 · Updated 1 time

Summary

This study tests whether combining two targeted drugs, ibrutinib and venetoclax, can shrink tumors in adults with Waldenström macroglobulinemia, a rare blood cancer. Participants must have a specific MYD88 gene mutation. The main goal is to see how many patients achieve a very good partial response within 24 treatment cycles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02214, United States

Conditions

Explore the condition pages connected to this study.