New pill tested as last hope for Tough-to-Treat skin cancer

NCT ID NCT02581930

Summary

This study is testing whether a pill called ibrutinib can help control advanced skin melanoma that has continued to grow despite standard immunotherapies and other targeted drugs. It involves 18 patients with stage IV melanoma who take the pill daily. The main goal is to see if the tumor shrinks and to understand how the drug works and why resistance might develop.

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Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Los Angeles General Medical Center

    Los Angeles, California, 90033, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • UCHealth University of Colorado Hospital

    Aurora, Colorado, 80045, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Virginia Cancer Center

    Charlottesville, Virginia, 22908, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.