Promising combo therapy targets aggressive lymphoma in young patients

NCT ID NCT02427620

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of targeted therapy (ibrutinib) and immunotherapy (rituximab) followed by strong chemotherapy in young patients with newly diagnosed mantle cell lymphoma, an aggressive blood cancer. The goal is to see if this approach improves response rates while managing side effects. About 131 participants will receive the treatment in a specific order to maximize cancer cell killing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

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