New drug combo shows promise for aggressive lymphoma in young patients

NCT ID NCT02427620

First seen Nov 21, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests whether giving a targeted drug (ibrutinib) plus an immunotherapy (rituximab) before standard chemotherapy can improve outcomes for young patients with newly diagnosed mantle cell lymphoma, an aggressive blood cancer. About 131 participants will receive the combination, followed by consolidation chemotherapy. The main goal is to see how many patients achieve complete or partial remission, while also monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.