New hope for hard-to-treat myeloma: drug trio shows promise in early trial

NCT ID NCT03702725

First seen Jan 10, 2026 · Last updated May 10, 2026 · Updated 14 times

Summary

This early-phase study tested a combination of three drugs (ibrutinib, lenalidomide, and dexamethasone) in 14 adults with multiple myeloma that had returned or stopped responding to prior treatments. The main goal was to find safe doses and identify side effects. While the approach aims to control the disease, ongoing treatment is typically needed, so this is not a cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MULTIPLE MYELOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • The Ohio State University Wexner Medical Center/James Cancer Hospital

    Columbus, Ohio, 43210, United States

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.