New drug combo shows promise for Tough-to-Treat leukemia

NCT ID NCT02997761

First seen Apr 24, 2026 · Last updated May 13, 2026 · Updated 4 times

Summary

This study tested a combination of two drugs, ibrutinib and blinatumomab, in 19 adults whose B-cell acute lymphoblastic leukemia (B-ALL) had returned or stopped responding to treatment. The goal was to see if the combination could improve remission rates. Participants received both drugs, and researchers measured how many achieved complete remission and monitored side effects.

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Contacts and locations

Locations

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

Conditions

Explore the condition pages connected to this study.