New stroke treatment targets Medium-Sized clots
NCT ID NCT07336927
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving a clot-busting drug directly into the brain artery, plus possibly removing the clot with a device, helps people with medium-sized stroke clots. About 614 participants who cannot receive standard IV clot-busters will be randomly assigned to either the new procedure or best medical care alone. The goal is to see if the procedure leads to better recovery and less disability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tenecteplase (TNK) given directly into the artery, plus possible mechanical clot removal
What this could lead to
If successful, this could offer a new treatment option for stroke patients with medium-sized clots who cannot receive standard clot-busting drugs through a vein.
What could go wrong
This is an early-stage trial with no phase assigned, so results are uncertain. The procedure carries risks like bleeding or vessel damage, and the benefit over standard care is not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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West China Hospital of Sichuan University
Chengdu, Sichuan, 610041, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••