Blood concentrate may supercharge gum repair — a trial puts it to the test
NCT ID NCT07722390
First seen Jul 23, 2026 · Last updated Jul 30, 2026 · Updated 3 times
Summary
This trial tests whether adding injectable platelet-rich fibrin (I-PRF) — a concentrate made from a patient's own blood — to standard minimally invasive gum cleaning can improve healing of deep periodontal defects. About 48 adults with advanced gum disease and at least one deep pocket will receive either the standard cleaning alone or cleaning plus an I-PRF injection into the defect. The main question is whether the added I-PRF leads to greater reduction in pocket depth over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- injectable platelet-rich fibrin (I-PRF) made from the patient's own blood
- What this could lead to
- If it works, this could offer a simple, natural way to improve gum healing and reduce pocket depth without surgery.
- What could go wrong
- This is a small, early-stage trial with only 48 participants. The benefit over standard care alone may be modest, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cairo University
RECRUITINGCairo, Egypt
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Other studies related to the condition(s) this trial covers.