Experimental drug for rare Skin-Lung disease fails to reach goal

NCT ID NCT04781543

First seen Mar 28, 2026 · Last updated May 16, 2026 · Updated 5 times

Summary

This study tested an experimental drug called HZN-825 in about 300 people with a rare autoimmune disease that causes skin thickening and can harm the lungs. The trial was stopped early, so results are not available. Participants took the drug or a placebo daily for up to 52 weeks to see if it improved lung function and skin symptoms.

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Contacts and locations

Locations

  • Hospital de La Santa Creu i Sant Pau

    Barcelona, 08025, Spain

  • Institute for Treatment and Rehabilitation Niska Banja

    Niška Banja, 708120, Serbia

  • Institute of Rheumatology - PPDS

    Belgrade, 11000, Serbia

  • Military Medical Academy

    Belgrade, 11000, Serbia

Conditions

Explore the condition pages connected to this study.