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New surgical approach aims to tame resistant hypertension

NCT ID NCT06216808

Recruiting now Disease control Sponsor: DeepQure Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study is testing a new device called HyperQure that uses radiofrequency energy to disrupt nerves around the kidney arteries, which may help lower blood pressure. It involves 10 adults with resistant hypertension who are already taking 3 or more blood pressure medications. The main goal is to see if the procedure is safe and if it reduces 24-hour blood pressure at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
HyperQure Renal Denervation System (a device that uses radiofrequency energy to disrupt nerves around the kidney arteries, done via laparoscopic surgery)
What this could lead to
If it works, this could offer a new way to lower blood pressure in people whose hypertension doesn't respond to multiple medications, potentially reducing their need for drugs.
What could go wrong
This is a very early, first-in-human study with only 10 participants, so results may not apply to everyone. The procedure is surgical and carries risks like infection or blood vessel damage, and it's unclear if the blood pressure drop will last.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

resistant hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESISTANT HYPERTENSION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

  • Chonnam National University Hospital Hwasun Hospital

    RECRUITING

    Jeonam, Chonnam Province, South Korea

    Contact Email: •••••@•••••

  • Hanyang University Seoul Hospital

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

  • Seoul National University Bundang Hospital

    RECRUITING

    Gyeonggi-do, South Korea

    Contact Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

  • Yonsei University Health System, Severance Hospital

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

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