Hydration hype: could more fluids save Kids' kidneys from e. coli?
NCT ID NCT05219110
First seen May 22, 2026 · Last updated May 22, 2026
Summary
This study tests whether giving children with a severe E. coli infection extra fluids through an IV can prevent kidney damage. About 1,040 children will be randomly assigned to either high-volume fluids or standard care. The goal is to see if this simple approach reduces the need for dialysis or long-term kidney problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alberta Children's Hospital
RECRUITINGCalgary, Alberta, T2N 1N4, Canada
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Arkansas Children's Hospital
RECRUITINGLittle Rock, Arkansas, 72202, United States
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229-3039, United States
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Children's Minnesota Hospital
RECRUITINGMinneapolis, Minnesota, 55404, United States
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Children's Research Institute
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Indiana University Children's Hospital
RECRUITINGIndianapolis, Indiana, 47401, United States
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McMaster University
RECRUITINGHamilton, Ontario, L8S 4K1, Canada
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
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Norton Children's Hospital
RECRUITINGLouisville, Kentucky, 40202, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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The Hospital for Sick Children
RECRUITINGToronto, Ontario, M5G 1X8, Canada
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University Hospitals Rainbow Babies & Children's Hospital
RECRUITINGCleveland, Ohio, 44106, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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University of Alberta
RECRUITINGEdmonton, Alberta, T5J 4P6, Canada
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University of California, Davis
RECRUITINGSacramento, California, 95817, United States
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University of California, San Diego
RECRUITINGLa Jolla, California, 92093, United States
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University of Colorado Denver
RECRUITINGDenver, Colorado, 80045, United States
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University of Kentucky
RECRUITINGLexington, Kentucky, 40526, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Vanderbilt Children's Hospital
RECRUITINGNashville, Tennessee, 43205, United States
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.