Can induced hypothermia after seizures save brains? new trial aims to find out

NCT ID NCT07383779

First seen Feb 03, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study tests whether lowering body temperature to about 33°C for 24 hours after severe, hard-to-stop seizures improves brain recovery at 90 days. It involves 466 adults on breathing machines, comparing cooling to standard temperature control. The goal is to see if cooling reduces brain damage and the need for strong sedative drugs.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Annecy Genevois

    Metz-Tessy, France

    Contact

  • CH Le Mans

    Le Mans, France

  • CH Melun-Sénart

    Melun, France

  • CH Simone Veil

    Cannes, France

    Contact

  • CH Sud Francilien

    Corbeil-Essonnes, France

    Contact

  • CH Versailles

    Le Chesnay, France

  • CHITS Toulon

    Toulon, France

  • CHR Orléans

    Orléans, France

    Contact

  • CHU Brest

    Brest, France

    Contact

  • CHU Dijon

    Dijon, France

  • CHU Nantes

    Nantes, France

  • CHU Rennes

    Rennes, France

  • GH Paris Saint-Joseph

    Paris, France

    Contact

  • Hôpital Ambroise Paré

    Boulogne-Billancourt, France

    Contact

  • Hôpital COCHIN

    Paris, France

  • Hôpital Edouard Herriot

    Lyon, France

    Contact

  • Hôpital Foch

    Suresnes, France

    Contact

  • Hôpital Hautepierre

    Strasbourg, France

    Contact

  • Hôpital Louis Mourier

    Colombes, France

    Contact

  • Hôpital de la Croix-Rousse

    Lyon, France

    Contact

Conditions

Explore the condition pages connected to this study.