How much enzyme does it take to erase a filler?
NCT ID NCT01722916
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study investigates the correct dose of hyaluronidase, an enzyme that breaks down hyaluronic acid fillers, to safely and effectively remove them. Researchers will inject increasing amounts of hyaluronidase into healthy adults until the filler is no longer detectable. The goal is to establish a standard dosing guide for doctors, reducing guesswork and improving safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyaluronidase
What this could lead to
If successful, this could provide clear dosing guidelines for safely dissolving unwanted hyaluronic acid fillers.
What could go wrong
This is a very small early-phase pilot study with only 5 participants, so results may not apply to everyone. Risks include allergic reactions or incomplete filler removal.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Northwestern University Department of Dermatology
Chicago, Illinois, 60611, United States