How much enzyme does it take to erase a filler?
NCT ID NCT01722916
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study investigates the correct dose of hyaluronidase, an enzyme that breaks down hyaluronic acid fillers, to safely and effectively remove them. Researchers will inject increasing amounts of hyaluronidase into healthy adults until the filler is no longer detectable. The goal is to establish a standard dosing guide for doctors, reducing guesswork and improving safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyaluronidase
- What this could lead to
- If successful, this could provide clear dosing guidelines for safely dissolving unwanted hyaluronic acid fillers.
- What could go wrong
- This is a very small early-phase pilot study with only 5 participants, so results may not apply to everyone. Risks include allergic reactions or incomplete filler removal.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern University Department of Dermatology
Chicago, Illinois, 60611, United States