Shoulder pain relief without surgery? hyaluronic acid injections under study
NCT ID NCT07699406
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This study investigates whether ultrasound-guided injections of low-molecular-weight hyaluronic acid (Hyalotend®) can safely reduce pain and improve shoulder function in people with chronic non-calcific supraspinatus tendinopathy. Participants receive two injections and are followed over time to track changes in pain, daily activities, and any side effects. The goal is to see if this treatment offers a non-surgical option for those who haven't found relief with physical therapy or medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Low-molecular-weight hyaluronic acid (Hyalotend®)
- What this could lead to
- If successful, this approach could offer a non-surgical treatment option for chronic shoulder tendon pain that hasn't improved with physical therapy or medication.
- What could go wrong
- This is a small, single-arm observational study with only 30 participants, so results may not apply broadly. The treatment may not provide lasting relief, and injection-related side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.