New immunotherapy shows promise in Hard-to-Treat colorectal cancer

NCT ID NCT05652894

Ongoing Disease control Sponsor: Taizhou Hanzhong biomedical co. LTD Source: ClinicalTrials.gov ↗

First seen Apr 29, 2026 · Last updated May 14, 2026 · Updated 3 times

Summary

This study tests a new immunotherapy drug, HX008, against standard chemotherapy for people with a specific type of advanced colorectal cancer (MSI-H/dMMR). The goal is to see if HX008 can slow cancer growth better than chemo. About 190 adults with this cancer type will be randomly assigned to receive either HX008 or chemotherapy, and their progress will be tracked over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Affiliated Cancer Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China
Affiliated Qidong Hospital of Nantong University

Nantong, Jiangsu, China
Anhui Provincial Cancer Hospital

Hefei, Anhui, China
Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, China
Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China
Cancer Hospital of Shandong First Medical University (Shandong Cancer Institute,Shandong Cancer Hospital)

Jinan, Shangdong, China
Changde First People's Hospital

Changde, Hunan, China
Chengdu Hospital of Integrated Traditional Chinese and Western Medicine

Chengdu, Sichuan, China
China-Japan Union Hospital of Jilin University

Changchun, Jilin, China
Dalian University of Technology Affiliated Central Hospital (Dalian Central Hospital)

Dalian, Shenyang, China
Deyang People's Hospital

Deyang, Sichuan, China
First Affiliated Hospital of Gannan Medical University

Ganzhou, Jiangxi, China
First Hospital of Shanxi Medical University

Taiyuan, Shanxi, China
Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China
Fujian Medical University Union Hospital

Fuzhou, Fujian, China
Gansu Provincial People's Hospital

Lanzhou, Gansu, China
Ganzhou Municipal Hospital

Ganzhou, Jiangxi, China
General Hospital of the Northern Theater Command of the Chinese People's Liberation Army

Shenyang, Liaoning, China
Guangxi Medical University Affiliated Tumor Hospital

Nanning, Guangxi, China
Guizhou Provincial People's Hospital

Guiyang, Guizhou, China
Henan Cancer Hospital

Zhengzhou, Henan, China
Huai'an First People's Hospital

Huaian, Jiangsu, China
Hubei Cancer Hospital

Wuhan, Hubei, China
Hunan Cancer Hospital

Changsha, Hunan, China
Jiangsu Cancer Hospital

Nanjing, Jiangsu, China
Jiangsu Province Hospital

Nanjing, Jiangsu, China
Liaoning Health Industry Group Fukuang General Hospital

Fushun, Liaoning, China
Meizhou People's Hospital(Huangtang Hospital)

Meizhou, Guangdong, China
Mianyang Central Hospital

Mianyang, Sichuan, China
Nanyang Central Hospital

Nanyang, Henan, China
Ningbo No.2 Hospital

Ningbo, Zhejiang, China
North Sichuan Medical College Affiliated Hospital

Nanchong, Sichuan, China
Peking Union Medical College Hospital

Beijing, Beijing Municipality, China
Peking University Cancer Hospital

Beijing, Beijing Municipality, China
Peking University First Hospital

Beijing, Beijing Municipality, China
Qilu Hospital of Shandong University

Jinan, Shangdong, China
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China
Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Xi'an, China
Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China
Shanxi Provincial Cancer Hospital

Taiyuan, Shanxi, China
Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China
Suzhou Ninth People's Hospotal

Suzhou, Jiangsu, China
The Affiliated Quzhou Hospital of Wenzhou Medical University

Quzhou, Zhejiang, China
The Eighth Affiliated Hospital of Southern Medical University

Foshan, Guangdong, China
The Fifth Affiliated Hospital of Anhui Medical University

Fuyang, Anhui, China
The Fifth People's Hospital Of Datong

Datong, Shanxi, China
The First Affiliated Hospital of Bengbu Medical University

Bengbu, Anhui, China
The First Affiliated Hospital of Chengdu Medical College

Chengdu, Sichuan, China
The First Affiliated Hospital of Henan University of Science and Technology

Luoyang, Henan, China
The First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China
The First Affiliated Hospital of Shantou University Medical College

Shantou, Guangdong, China
The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Xi'an, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China
The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China
The First Hospital of China Medical University

Shenyang, Liaoning, China
The Second Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China
The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China
The Second People's Hospital of nayang City

Nanchangcun, Henan, China
The Second Xiangya Hospital of Central South University

Changsha, Hunan, China
The Sixth Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China
Tianjin People's Hospital

Tianjin, Tianjin Municipality, China
Wuhan Central Hospital

Wuhan, Hubei, China
Xuzhou Central Hospital

Xuzhou, Jiangsu, China

Conditions

Explore the condition pages connected to this study.

METASTATIC COLORECTAL CANCER