Experimental drug aims to sharpen minds in Huntington's disease

NCT ID NCT05107128

Completed Symptom relief Sponsor: Supernus Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether an investigational drug called SAGE-718 could improve thinking skills like memory, attention, and problem-solving in people with Huntington's disease. It involved 189 participants with mild-to-moderate cognitive impairment who took either the drug or a placebo for several months. The main goal was to see if the drug helped people perform better on standard tests of mental speed and daily functioning.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Sage Investigational Site

Little Rock, Arkansas, 72205, United States
Sage Investigational Site

La Jolla, California, 92037, United States
Sage Investigational Site

Los Angeles, California, 90095, United States
Sage Investigational Site

Sacramento, California, 95817, United States
Sage Investigational Site

Englewood, Colorado, 80113, United States
Sage Investigational Site

Washington D.C., District of Columbia, 20007, United States
Sage Investigational Site

Boca Raton, Florida, 33431, United States
Sage Investigational Site

Boca Raton, Florida, 33486, United States
Sage Investigational Site

Tampa, Florida, 33612, United States
Sage Investigational Site

Honolulu, Hawaii, 96817, United States
Sage Investigational Site

Chicago, Illinois, 60611, United States
Sage Investigational Site

Chicago, Illinois, 60612, United States
Sage Investigational Site

Indianapolis, Indiana, 46202, United States
Sage Investigational Site

Iowa City, Iowa, 52242, United States
Sage Investigational Site

Kansas City, Kansas, 66160, United States
Sage Investigational Site

Baltimore, Maryland, 21287, United States
Sage Investigational Site

Boston, Massachusetts, 02129, United States
Sage Investigational Site

Boston, Massachusetts, 02215, United States
Sage Investigational Site

Farmington Hills, Michigan, 48334, United States
Sage Investigational Site

Buffalo, New York, 14221, United States
Sage Investigational Site

New York, New York, 10032, United States
Sage Investigational Site

Chapel Hill, North Carolina, 27599, United States
Sage Investigational Site

Durham, North Carolina, 27705, United States
Sage Investigational Site

Cincinnati, Ohio, 45219, United States
Sage Investigational Site

Toledo, Ohio, 43614, United States
Sage Investigational Site

Philadelphia, Pennsylvania, 19107, United States
Sage Investigational Site

Charleston, South Carolina, 29425, United States
Sage Investigational Site

Memphis, Tennessee, 38157, United States
Sage Investigational Site

Nashville, Tennessee, 37212, United States
Sage Investigational Site

Houston, Texas, 77030, United States
Sage Investigational Site

Richmond, Virginia, 23298, United States
Sage Investigational Site

Kirkland, Washington, 98034, United States
Sage Investigational Site

Spokane, Washington, 99202, United States
Sage Investigational Site

Madison, Wisconsin, 53792, United States
Sage Investigational Site

Westmead, New South Wales, 2145, Australia
Sage Investigational Site

Herston, Queensland, 4029, Australia
Sage Investigational Site

Bethlehem, Victoria, 3162, Australia
Sage Investigational Site

Nedlands, Western Australia, 6009, Australia
Sage Investigational Site

Halifax, Nova Scotia, B3S 1N2, Canada
Sage Investigational Site

North York, Ontario, M2K 1E1, Canada
Sage Investigational Site

Montreal, Quebec, H2X 0A9, Canada
Sage Investigational Site

Tooting, London, SW17 0QT, United Kingdom
Sage Investigational Site

Aberdeen, AB25 2ZA, United Kingdom
Sage Investigational Site

Birmingham, B15 2FG, United Kingdom
Sage Investigational Site

Cardiff, CF10 3AX, United Kingdom
Sage Investigational Site

Leeds, LS7 4SA, United Kingdom
Sage Investigational Site

Newcastle upon Tyne, NE6 4QD, United Kingdom
Sage Investigational Site

Plymouth, PL6 8BT, United Kingdom
Sage Investigational Site

Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.

HUNTINGTON'S DISEASE