New brain scans aim to catch Huntington's cognitive decline early

This study aims to create more sensitive cognitive tests for Huntington's disease by combining brain imaging (PET and MRI) with blood markers. Researchers will study 90 participants—healthy controls, pre-symptomatic gene carriers, and early-stage patients—to understand how brain changes relate to thinking skills. The goal is to detect subtle cognitive problems earlier and better classify different types of cognitive decline, which could help future treatment trials.