Withdrawn trial aimed to stop bodies from fighting rare disease drug

NCT ID NCT05494593

Summary

This study aimed to see if a combination of immune-suppressing drugs could help young boys with Hunter syndrome better tolerate their main enzyme replacement therapy (ELAPRASE). The goal was to prevent their immune systems from developing antibodies that could block the treatment's effectiveness. The trial was withdrawn before any participants were enrolled.

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Contacts and locations

Locations

  • Ann and Robert H Lurie Childrens Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • Children's Hospital and Research Center at Oakland

    Oakland, California, 94609, United States

  • Children's Hospitals and Clinics of Minnesota

    Minneapolis, Minnesota, 55404, United States

  • NewYork-Presbyterian Morgan Stanley Children's Hospital

    New York, New York, 10032, United States

  • Phoenix Childrens Hospital

    Phoenix, Arizona, 85016, United States

  • Rady Childrens Hospital San Diego - PIN

    San Diego, California, 92123, United States

  • The Cleveland Clinic Foundation

    Twinsburg, Ohio, 44087, United States

  • The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Center

    Torrance, California, 90502, United States

Conditions

Explore the condition pages connected to this study.