Blood markers may predict drug resistance in rare blood cancer

NCT ID NCT05853458

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study looked at whether two simple blood test results—hemoglobin and red blood cell distribution width—can predict if a person with polycythemia vera will stop responding to the drug hydroxyurea. Researchers used a computer model to identify these markers and then tested them in 76 patients starting treatment. The goal was to help doctors choose better treatments earlier for those likely to fail standard therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POLYCYTHEMIA VERA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Novartis Investigative Site

    Heidelberg, Baden-Wurttemberg, 69115, Germany

  • Novartis Investigative Site

    Kronach, Bavaria, 96317, Germany

  • Novartis Investigative Site

    Straubing, Bavaria, 94315, Germany

  • Novartis Investigative Site

    Langen, Hesse, 63225, Germany

  • Novartis Investigative Site

    Lingen Ems, Lower Saxony, 49808, Germany

  • Novartis Investigative Site

    Aachen, North Rhine-Westphalia, 52064, Germany

  • Novartis Investigative Site

    Cologne, North Rhine-Westphalia, 50674, Germany

  • Novartis Investigative Site

    Dortmund, North Rhine-Westphalia, 44309, Germany

  • Novartis Investigative Site

    Velbert, North Rhine-Westphalia, 42551, Germany

  • Novartis Investigative Site

    Saarbrücken, Saarland, 66113, Germany

  • Novartis Investigative Site

    Merseburg, Saxony-Anhalt, 06217, Germany

  • Novartis Investigative Site

    Berlin, 10407, Germany

  • Novartis Investigative Site

    Donauwörth, 86609, Germany

  • Novartis Investigative Site

    Dresden, 01307, Germany

  • Novartis Investigative Site

    Erding, 85435, Germany

  • Novartis Investigative Site

    Gütersloh, 33332, Germany

  • Novartis Investigative Site

    Hanover, 30161, Germany

  • Novartis Investigative Site

    Kiel, 24105, Germany

  • Novartis Investigative Site

    Mutlangen, 73557, Germany

  • Novartis Investigative Site

    Naunhof, 04683, Germany

  • Novartis Investigative Site

    Würselen, 52146, Germany

Conditions

Explore the condition pages connected to this study.