New shot combo aims to tame hepatitis b
NCT ID NCT07183306
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial tests two new injections (HT-101 and HT-102) in 86 people with chronic hepatitis B. Participants receive the shots every 4 weeks, along with standard antiviral pills. The main goal is to check safety and how the body processes the drugs, while also looking at whether they can lower hepatitis B virus levels. It's too early to know if this will be a better treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HT-101 and HT-102 injections
- What this could lead to
- If successful, this could lead to a new way to control chronic hepatitis B, possibly reducing the need for lifelong daily pills.
- What could go wrong
- This is an early (Phase 1/2) and small trial (86 people), so safety and effectiveness are not yet proven. The treatment may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Ditan Hospital Capital Medical University
Beijing, Beijing Municipality, 100015, China
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Guangzhou Eighth People's Hospital, Guangzhou Medical University
Guangzhou, Guangdong, 510440, China
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Nanfang Hospital
Guangzhou, Guangdong, 510515, China
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Qingyuan People's Hospital
Qingyuan, Guangdong, 511518, China
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Shanghai Public Health Clinical Center
Shanghai, Shanghai Municipality, 200083, China
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Sichuan Provincial People's Hospital
Chengdu, Sichuan, 610072, China
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Xiamen Hospital of Traditional Chinese Medicine
Xiamen, Fujian, 361001, China
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