New psoriasis cream shows early promise in small trial
NCT ID NCT07623486
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new cream called HSK44459 in healthy volunteers and people with plaque psoriasis. The first part checks safety and how the body processes the cream. The second part looks at whether different strengths of the cream can improve psoriasis symptoms over 8 weeks. About 180 participants are involved, and the cream is compared to a placebo (inactive cream).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HSK44459 cream
What this could lead to
If it works, this could point toward a new topical treatment for plaque psoriasis that reduces skin plaques and symptoms.
What could go wrong
This is an early Phase I/II trial with a small number of participants. The cream may not prove effective or safe in larger studies, and side effects are still being evaluated.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hangzhou First People's Hospital
Hangzhou, Zhejiang, China