New breast cancer drug challenger aims to match standard treatment

NCT ID NCT04514419

First seen Nov 21, 2025 · Last updated May 14, 2026 · Updated 24 times

Summary

This study tests whether a new drug called HS627 works as well as the approved drug pertuzumab when both are given with trastuzumab and chemotherapy before surgery for early or locally advanced HER2-positive breast cancer. About 408 participants will receive either HS627 or pertuzumab for four cycles. The main goal is to see if the cancer disappears completely in the breast tissue at the time of surgery.

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Contacts and locations

Locations

  • The Affiliated Hospital of Qingdao University

    Qingdao, Shandong, 266000, China

Conditions

Explore the condition pages connected to this study.