New injection could help heart failure patients shed excess fluid
NCT ID NCT06506994
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tested a new drug called HRS-9057 in 25 adults with chronic heart failure who still had fluid buildup despite standard diuretics. The drug was given as an injection and compared to tolvaptan pills. The main goal was to check safety and how well the drug removes extra fluid, aiming to reduce swelling and improve comfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HRS-9057 injection
What this could lead to
If it works, this could lead to a new option for heart failure patients to safely get rid of extra fluid and reduce swelling.
What could go wrong
This is a very early Phase 1 study with only 25 people, so safety and effectiveness are not yet proven. The drug may not work better than existing treatments or could have unexpected side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Second Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, 510285, China