New pill offers hope for PNH patients still anemic on standard therapy

NCT ID NCT06715943

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 18 times

Summary

This study tested an experimental pill called HRS-5965 in 39 adults with paroxysmal nocturnal hemoglobinuria (PNH) who remained anemic despite using standard anti-C5 antibody drugs. The goal was to see if the pill could raise hemoglobin levels without needing blood transfusions. Participants took the capsule for 24 weeks, and researchers measured blood counts and safety.

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Contacts and locations

Locations

  • Hematology Hospital of Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 30000, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 30000, China

Conditions

Explore the condition pages connected to this study.