Can a broader HPV vaccine boost protection after the original shot?
NCT ID NCT07530679
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test if giving a 9-valent HPV vaccine to women who previously received the bivalent HPV vaccine is safe and boosts their immune response. Researchers will enroll 360 healthy women aged 18-45 and compare two different dosing schedules (two doses vs. three doses) against a standard three-dose schedule in women not previously vaccinated. The goal is to see if the broader vaccine can provide additional protection against more HPV types.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 9-valent human papillomavirus vaccine
- What this could lead to
- If successful, this could show that a single booster or two-dose schedule of the 9-valent HPV vaccine is safe and effective for women already vaccinated with the bivalent vaccine, potentially simplifying future vaccination programs.
- What could go wrong
- This is an early-stage, open-label study with only 360 participants, so results may not apply to everyone. The study is not yet recruiting, and the immune response measured may not directly translate to long-term cancer prevention.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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