One shot may be enough: HPV vaccine study could change guidelines

NCT ID NCT07314307

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a single dose of the HPV vaccine (Gardasil 9) can protect young women from HPV infection. Over 150,000 women in Sweden are participating, receiving one vaccine dose along with routine screening. The goal is to see if one dose is effective enough to help eliminate HPV and reduce cervical cancer risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Gardasil 9 (HPV vaccine)

What this could lead to

If one dose works as well as the full series, it could simplify HPV vaccination, making it easier and cheaper to prevent cervical cancer.

What could go wrong

This is an observational study, not a randomized trial, so results may be less definitive. The study only follows women for 3 years, so long-term protection is unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

human papilloma virus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karolinska University Hospital

    Stockholm, Sweden