Could a single HPV shot slash cervical cancer in africa?
NCT ID NCT02834637
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study in Tanzania tests whether one dose of the HPV vaccine works as well as the standard two or three doses in girls aged 9-14. Cervical cancer is a major killer in East Africa, and reducing the number of shots could cut costs and make vaccination more accessible. The trial will compare immune responses from different dose schedules over several years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HPV vaccine (bivalent or nonavalent)
What this could lead to
If successful, this could show that a single dose of HPV vaccine is enough to protect against cervical cancer, making vaccination cheaper and easier to deliver in low-resource areas.
What could go wrong
This is a Phase 3 trial, but results are based on immune responses, not actual cancer prevention. Infections like malaria may affect vaccine effectiveness, and long-term protection is still being studied.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mwanza Intervention Trials Unit (MITU)
Mwanza, Tanzania