Engineered immune cells take on HPV cancers in early trial

NCT ID NCT03578406

First seen Jan 21, 2026 · Last updated Jun 08, 2026 · Updated 27 times

Summary

This early-stage trial tested a new treatment for people with HPV16-positive head and neck or cervical cancer that has spread or come back. The therapy uses a patient's own immune cells, modified to recognize and attack HPV-infected cancer cells, with some cells also engineered to release an anti-PD1 substance to boost their effectiveness. Nine participants received different doses to find the safest amount, and the study is now complete.

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Contacts and locations

Locations

  • Qingzhu Jia

    Chongqing, Chongqing Municipality, 400037, China

Conditions

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