HPV linked to rare sinonasal cancers in new study

NCT ID NCT04979000

Completed Knowledge-focused Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 49 people with sinonasal cancer to see if high-risk HPV, tobacco, alcohol, or drug use play a role. Researchers tested tumor samples for HPV and compared risk factors by gender and race. The goal is to better understand what causes these rare cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could clarify how HPV and lifestyle factors contribute to sinonasal cancers, potentially guiding future prevention or screening strategies.

What could go wrong

This is a small, completed observational study (49 participants) that looks back at existing data, so it cannot prove cause and effect or directly lead to a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

human papillomavirus-related squamous cell carcinoma nasal cavity and paranasal sinus carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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Locations

Johns Hopkins University

Baltimore, Maryland, 21287, United States