Engineered immune cells take on HPV cancers in early trial

NCT ID NCT03578406

First seen Jan 21, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This early-stage trial tested a new treatment for people with HPV16-positive head and neck or cervical cancer that had spread or come back. The therapy uses a patient's own immune cells, specially trained to recognize and attack HPV-infected cancer cells. Some of these cells were also designed to release a substance that blocks a common cancer defense mechanism. The main goal was to find the safest dose, and only 9 people took part.

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Contacts and locations

Locations

  • Qingzhu Jia

    Chongqing, Chongqing Municipality, 400037, China

Conditions

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