New oral pill HPP737 aims to clear psoriasis in phase 3 trial
NCT ID NCT07712705
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This Phase 3 trial tests whether an oral drug called HPP737 can safely improve moderate-to-severe plaque psoriasis in adults. Participants take HPP737 or a placebo daily for 16 weeks, with doctors measuring skin clearance using standard scores like PASI. The study aims to see if HPP737 helps more people achieve significant skin improvement compared to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental oral drug called HPP737
- What this could lead to
- If successful, HPP737 could offer a new oral treatment option for people with moderate-to-severe plaque psoriasis, potentially improving skin clearance and quality of life.
- What could go wrong
- This is a Phase 3 trial, but results may not confirm benefit over placebo. Side effects are possible, and the drug may not work for everyone or may have safety issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital of Chengde Medical College
Chengde, China
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Affiliated Hospital of Guilin Medical University
Guilin, China
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Affiliated Hospital of Jiangsu University
Zhenjiang, China
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Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine
Tianjin, China
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Beijing Friendship Hospital, Capital Medical University
Beijing, China
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Beijing Tongren Hospital, Capital Medical University
Beijing, China
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Cangzhou People's Hospital
Cangzhou, China
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Chengdu Second People's Hospital
Chengdu, China
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Dermatology Hospital, Southern Medical University
Guangzhou, China
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Dongguan First People's Hospital
Dongguan, China
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General Hospital of Ningxia Medical University
Yinchuan, China
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Guangdong Provincial People's Hospital
Guangzhou, China
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Hangzhou First People's Hospital
Hangzhou, China
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Hangzhou Third People's Hospital
Hangzhou, China
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Jiangxi Provincial Dermatology Hospital
Nanchang, China
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Jiangyin Hospital of Traditional Chinese Medicine
Wuxi, China
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Jiaxing First Hospital
Jiaxing, China
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Jinan Central Hospital
Jinan, China
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Lianyungang First People's Hospital
Lianyungang, China
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Nanyang Central Hospital
Nanyang, China
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Nanyang First People's Hospital
Nanyang, China
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Peking University People's Hospital
Beijing, China
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Shandong Provincial Hospital
Jinan, China
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Shandong Provincial Hospital of Dermatology
Guiyang, China
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Shandong Provincial Hospital of Dermatology
Jinan, China
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Shanghai Skin Disease Hospital
Shanghai, China
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Shengli Oilfield Central Hospital
Dongying, China
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Shiyan People's Hospital
Shiyan, China
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Suining Central Hospital
Suining, China
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The First Affiliated Hospital of Bengbu Medical College
Bengbu, China
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The First Affiliated Hospital of Gannan Medical University
Gannan, China
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The First Affiliated Hospital of Kunming Medical University
Kunming, China
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, China
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The First Hospital of Hebei Medical University
Shijiazhuang, China
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The Second Affiliated Hospital of Harbin Medical University
Harbin, China
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The Second Affiliated Hospital of Xiamen Medical College
Xiamen, China
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The Second Hospital of Jilin University
Changchun, China
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The Second Xiangya Hospital of Central South University
Changsha, China
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The Sixth Affiliated Hospital of Sun Yat-sen University
Guangzhou, China
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The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, China
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The Third Xiangya Hospital of Central South University
Changsha, China
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Wuhan First Hospital
Wuhan, China
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Wuxi Second People's Hospital
Wuxi, China
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Xiangya Hospital, Central South University
Changsha, China
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Xianyang Hospital of Yan'an University
Xianyang, China
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Yancheng First People's Hospital
Yancheng, China
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Yantai Yuhuangding Hospital
Yantai, China
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Yijishan Hospital of Wannan Medical College
Wuhu, China
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM
Shanghai, China
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Zhejiang Provincial People's Hospital
Hangzhou, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Laser boost for stubborn psoriasis on hands and feet
- New oral pill HPP737 takes on psoriasis in Head-to-Head trial
- Psoriasis Patients' quality of life under the microscope
- Skin disease evolution under the microscope: a 17-Year look at what drives severity
- New oral pill HPP737 aims to clear psoriasis in phase II trial