New hope for Hard-to-Treat myeloma: early trial of HPN217 underway
NCT ID NCT04184050
First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 21 times
Summary
This early-stage study is testing a new drug called HPN217 (also known as MK-4002) in about 100 people whose multiple myeloma has returned or no longer responds to standard treatments. The main goals are to check the drug's safety, find the best dose, and see how the body processes it. This is not a cure, but a step toward better controlling this blood cancer.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Centre Hospitalier Universitaire De Nantes
Nantes, 44093, France
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Centre Hospitalier Universitaire de Poitiers
Poitiers, 86021, France
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Hospital Universitario Fundacion Jimenez Diaz (UAM-FJD)
Madrid, 28040, Spain
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Josep Carreras Leukaemia Research Institute
Barcelona, 08916, Spain
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Mayo Clinic Arizona
Phoenix, Arizona, 85054, United States
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OHSU
Portland, Oregon, 97239, United States
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14263, United States
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The University of Kansas Cancer Center
Fairway, Kansas, 66205, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of Rochester James P Wilmot Cancer Institute
Rochester, New York, 14642, United States
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University of Washington - Seattle Cancer Center Alliance
Seattle, Washington, 98109, United States
Conditions
Explore the condition pages connected to this study.