Does this everyday ingredient mess with your meds?
NCT ID NCT04534153
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether sodium lauryl sulfate (SLS), a common ingredient in many drug products, changes how the allergy drug fexofenadine (Allegra) is absorbed in the body. Twelve healthy adults took fexofenadine alone or with low or high amounts of SLS. Researchers measured drug levels in the blood and stool to see if SLS affects absorption.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sodium lauryl sulfate (SLS) added to fexofenadine (Allegra)
- What this could lead to
- If it works, this could help design better drug formulations that avoid unintended changes in drug absorption.
- What could go wrong
- This is a very small, early-phase study in 12 healthy people, so results may not apply to other drugs or populations. It only looks at absorption, not safety or effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for THE IMPACT OF EXCIPIENTS ON DRUG ABSORPTION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Ucsf Ctsi Crc
San Francisco, California, 94143, United States