Mayo clinic launches study on hormone therapy's impact on muscle in transgender individuals
NCT ID NCT06083766
First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times
Summary
This study from Mayo Clinic looks at how gender-affirming hormone therapy (GAHT) changes muscle metabolism and function in transgender and gender diverse people. Researchers will measure muscle energy use and overall physical health in 24 adults aged 18-40 who have been on GAHT for at least 10 months. The goal is to better understand the body's response to hormone therapy, not to test a new drug or treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gender-affirming hormone therapy
- What this could lead to
- If successful, this study could help doctors better understand how hormone therapy affects muscle health, potentially improving care for transgender and gender diverse people.
- What could go wrong
- This is a small, early-stage observational study with only 24 participants. It is designed to gather knowledge, not to test a new treatment, so direct health benefits are not guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States