Mayo clinic launches study on hormone therapy's impact on muscle in transgender individuals
NCT ID NCT06083766
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study from Mayo Clinic looks at how gender-affirming hormone therapy (GAHT) changes muscle metabolism and function in transgender and gender diverse people. Researchers will measure muscle energy use and overall physical health in 24 adults aged 18-40 who have been on GAHT for at least 10 months. The goal is to better understand the body's response to hormone therapy, not to test a new drug or treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gender-affirming hormone therapy
What this could lead to
If successful, this study could help doctors better understand how hormone therapy affects muscle health, potentially improving care for transgender and gender diverse people.
What could go wrong
This is a small, early-stage observational study with only 24 participants. It is designed to gather knowledge, not to test a new treatment, so direct health benefits are not guaranteed.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••