New drug could cool debilitating hot flashes for breast cancer survivors

NCT ID NCT05587296

Summary

This study is testing a new drug called elinzanetant to see if it can reduce the number and severity of hot flashes experienced by women with hormone-positive breast cancer who are taking anti-cancer therapy. About 474 women will take either the study drug or a placebo (a pill with no medicine) for one year, tracking their symptoms in a daily diary. The goal is to improve quality of life and help women stay on their essential cancer treatment by managing this common and disruptive side effect.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AKH Wien | Allg. Gynaekologie & gynaekologische Onkologie

    Vienna, 1090, Austria

  • Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Tenon - Gynecologie Obstetrique Medecine de la Reproduction

    Paris, 75020, France

  • Assuta Ashdod Public Hospital (R.A)

    Ashdod, 7747629, Israel

  • Axon Kft.

    Kecskemét, 6000, Hungary

  • Azienda Ospedaliera Ordine Mauriziano Di Torino - Ostetricia e Ginecologia

    Turin, Piedmont, 10128, Italy

  • Azienda Ospedaliera Universitaria Federico II Di Napoli - DAI Materno Infantile

    Naples, Campania, 80131, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona_Borgo Trento - Ostetricia e Ginecologia B

    Verona, Veneto, 37126, Italy

  • Azienda Ospedaliero Universitaria di Modena_Policlinico - Oncologia

    Modena, Emilia-Romagna, 41124, Italy

  • CHU Saint-Pierre/UMC Sint-Pieter

    Bruxelles - Brussel, 1000, Belgium

  • CHULN - H. Sta.Maria (Centro de Investigacao Clinica)

    Lisbon, 1649-035, Portugal

  • CHUSJ - Hospital Sao Joao

    Porto, 4200-319, Portugal

  • CLINICAL MEDICAL RESEARCH Sp. z o. o.

    Katowice, 40-156, Poland

  • CU Saint-Luc/UZ St-Luc

    Bruxelles - Brussel, 1200, Belgium

  • Careggi University Hospital - Ostetricia e Ginecologia

    Florence, Tuscany, 50134, Italy

  • Centre de Lutte Contre le Cancer François Baclesse - Service Pathologie mammaire

    Caen, 14000, France

  • Centre de Recherche du Centre Hospitalier de l'Universite de Montreal (CRCHUM)

    Montreal, Quebec, H2X 0A9, Canada

  • Centro Clinico Academico Braga | Braga, Portugal

    Braga, 4710-243, Portugal

  • Centro Hospitalar Universitario do Porto

    Porto, 4050-651, Portugal

  • Centro Hospitalar e Universitario de Coimbra, E.P.E. | Department of Gynecology

    Coimbra, 3000-075, Portugal

  • Centrum Badawcze Wspolczesnej Terapii

    Warsaw, 02-679, Poland

  • Centrum Medyczne Pratia Poznan

    Skorzewo, 60-185, Poland

  • Chaim Sheba Medical Center

    Ramat Gan, 5266202, Israel

  • Companhia Uniao Fabril | Hospital CUF Porto - Clinical Trials Department

    Porto, 4100-180, Portugal

  • Complexo Hospitalario Universitario De Santiago | Oncologia

    Santiago de Compostela, A Coruña, 15706, Spain

  • Cork University Hospital

    Cork, T12DC4A, Ireland

  • Debreceni Egyetem Klinikai Kozpont

    Debrecen, 4032, Hungary

  • Docrates Mehiläinen Syöpäsairaala

    Helsinki, 00180, Finland

  • Eberhard-Karls-Universität Tübingen

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • Evangelisches Krankenhaus Bergisch Gladbach - Gynäkologi

    Bergisch Gladbach, North Rhine-Westphalia, 51465, Germany

  • Femicare vzw | Tienen, BE

    Tienen, 3300, Belgium

  • Fondazione IRCCS Policlinico San Matteo - Ostetricia e Ginecologia

    Pavia, Lombardy, 27100, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Ginecologia Oncologica

    Rome, Lazio, 00168, Italy

  • Frauenarztpraxis Dr. Inka Kiesche

    Halle, Saxony-Anhalt, 6110, Germany

  • Frauenärzte am Schloss Borbeck

    Essen, North Rhine-Westphalia, 45355, Germany

  • Fundacao Champalimaud | Centro Clinico Champalimaud - Unidade Investigacao Clinica

    Lisbon, 1400-038, Portugal

  • Gabinet Ginekologiczny Janusz Tomaszewski

    Bialystok, 15-224, Poland

  • Ghent University Hospital | Women's Clinic Department

    Ghent, 9000, Belgium

  • Gynäkologisches Zentrum Bonn

    Bonn, North Rhine-Westphalia, 53111, Germany

  • Hadassah Hebrew University Hospital Ein Kerem

    Jerusalem, 9112001, Israel

  • Health Corporation of Galilee Medical Center

    Nahariya, 2210001, Israel

  • Hospital Clinico Universitario De Valencia | Ginecologia

    Valencia, 46010, Spain

  • Hospital General Universitario De Valencia | Ginecologia

    Valencia, 46014, Spain

  • Hospital General Universitario Gregorio Maranon | Oncologia

    Madrid, 28009, Spain

  • Hospital Universitario Virgen De Las Nieves | Oncologia Medica

    Granada, 18014, Spain

  • Hospital Universitario Virgen Del Rocio S.L. | Oncologia

    Seville, 41013, Spain

  • Hospital del Mar I Ginecologia

    Barcelona, 08003, Spain

  • Hôpital Erasme/Erasmus Ziekenhuis

    Brussels, 1070, Belgium

  • Hôpital Saint Louis

    Paris, 75010, France

  • ICANS - Institut de Cancerologie de Strasbourg Europe

    Strasbourg, 67033, France

  • ICO Site Paul Papin - Angers - Service Oncologie

    Angers, 49100, France

  • IRCCS Ospedale Policlinico San Martino - Clinica ostetrica e ginecologica

    Genoa, Liguria, 16132, Italy

  • Imperial College Healthcare NHS Trust| Queen Charlotte's and Chelsea Hospital - Gynaecology

    London, Greater London, W12 0NN, United Kingdom

  • Institut Bergonie - Unicancer Nouvelle Aquitaine

    Bordeaux, 33076, France

  • Institut de Cancerologie Ouest - Saint-Herblain - Service gynecologie medicale

    Saint-Herblain, 44800, France

  • Institut du Cancer de Montpellier - Val d'Aurelle - Service Oncogynecologie et senologie

    Montpellier, 34090, France

  • Istituto Europeo di Oncologia s.r.l - Ginecologia Preventiva

    Milan, Lombardy, 20141, Italy

  • Kazakh Institute of Oncology and Radiology - Department of Gynecology

    Almaty, 640000, Kazakhstan

  • Klinische Forschung Berlin-Mitte GmbH

    Berlin, 10117, Germany

  • Klinische Forschung Hannover-Mitte GmbH

    Hanover, Lower Saxony, 30159, Germany

  • La Zarzuela University Hospital | Ginecologia

    Aravaca, Madrid, 28023, Spain

  • Liverpool Women's NHS Foundation Trust | Liverpool Women's Hospital - Gynaecology

    Liverpool, Merseyside, L8 7SS, United Kingdom

  • Luz Saude | Hospital Beatriz Angelo - Centro de Investigacao Clinica

    Loures, Lisbon District, 2674-514, Portugal

  • Luz Saude | Hospital da Luz Lisboa - Centro de Investigacao Clinica

    Lisbon, 1500-650, Portugal

  • Lääkärikeskus Gyneko Oy

    Oulu, 90100, Finland

  • Mater Misericordiae University Hospital

    Dublin, D07R2WY, Ireland

  • MedUni Innsbruck | Brust Gesundheit Zentrum

    Innsbruck, Tyrol, 6020, Austria

  • Medical University of Graz | Division of Gynecology and Obstetrics

    Graz, Styria, 8036, Austria

  • Medplus Nordrhein

    Krefeld, North Rhine-Westphalia, 47799, Germany

  • Mehiläinen Kuopio

    Kuopio, 70100, Finland

  • Meir Medical Center

    Kfar Saba, 4428164, Israel

  • Multidisciplinary Medical Center of the Akimat of Astana - Department of Chemotherapy No1

    Astana, 010000, Kazakhstan

  • NHS Grampian | Aberdeen Royal Infirmary - Gynaecology

    Aberdeen, AB25 2ZN, United Kingdom

  • NHS Greater Glasgow and Clyde | Glasgow Royal Infirmary - Gynaecology

    Glasgow, Scotland, G4 0SF, United Kingdom

  • NZOZ MEDEM Wilk Sp. j.

    Katowice, 40-301, Poland

  • Pratia McM Kraków

    Krakow, 30-727, Poland

  • Praxis Hr. Dr. S. Fiedler

    Aachen, North Rhine-Westphalia, 52074, Germany

  • Praxis f. Gynäkologie und Geburtshilfe

    Bernburg, Saxony-Anhalt, 6406, Germany

  • Praxisklinik am Rosengarten

    Mannheim, Baden-Wurttemberg, 68165, Germany

  • Prywatny Gabinet Lekarski Ginekologia, Poloznictwo i Ultr.

    Lodz, 90-602, Poland

  • Rub-Int Noi Egeszsegcentrum

    Székesfehérvár, 8000, Hungary

  • S.C Ovidius Clinical Hospital SRL - Oncology Department

    Ovidiu, 905900, Romania

  • S.C. Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL

    Brasov, 500283, Romania

  • S.C. Quantum Medical Center SRL

    Bucharest, 012071, Romania

  • Salve Medica Sp. z o.o. SP.K.

    Lodz, 91-211, Poland

  • Sc Oncolab Srl

    Craiova, Dolj, 200385, Romania

  • Spitalul Clinic Filantropia

    Bucharest, 11132, Romania

  • St James' Hospital

    Dublin, D08NHY1, Ireland

  • St Vincents University Hospital

    Dublin, TBC, Ireland

  • Surrey and Sussex Healthcare NHS Trust - East Surrey Hospital - Gynaecology

    Redhill, Surrey, RH1 5RH, United Kingdom

  • Synexus Frankfurt Clinical Research Centre

    Frankfurt am Main, Hesse, 60313, Germany

  • Szabolcs Szatmr Bereg County University Teaching Hospital | Andras Jasa Teaching Hospital - Oncology

    Nyíregyháza, 4400, Hungary

  • Tampere University Hospital, Tampereen yliopistollinen sairaala (TAYS)

    Tampere, 33520, Finland

  • Tel-Aviv Sourasky Medical Center

    Tel Aviv, 6492601, Israel

  • The Ottawa Hospital - Riverside Campus

    Ottawa, Ontario, K1H 7W9, Canada

  • UNICANCER - Centre Leon-Berard (CLB) - Medical oncology

    Lyon, 69373, France

  • UZ Leuven Gasthuisberg

    Leuven, 3000, Belgium

  • Unidade Local De Saúde De Lisboa Ocidental E.P.E.

    Lisbon, 1449-005, Portugal

  • University College Hospital Galway

    Galway, H91YR71, Ireland

  • University Hospital Waterford

    Waterford, X91 ER8E, Ireland

  • Vaasa Central Hospital, Vaasan keskussairaala - Syöpätaudit

    Vaasa, 65130, Finland

  • ZAS Augustinus - Gynaecology department

    Wilrijk, Antwerpen, 2610, Belgium

  • Ziekenhuis Oost-Limburg - Gynecology Department

    Genk, 3600, Belgium

Conditions

Explore the condition pages connected to this study.