Scientists seek genetic clues to mysterious immune defects

NCT ID NCT00001355

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 5 times

Summary

This study looks at people with unusual or repeated infections and their family members to find the genetic and biochemical causes of immune system problems. Researchers will collect blood, saliva, urine, and other samples over time to better understand these conditions. The goal is to improve diagnosis and treatment for inherited immune defects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could lead to better diagnostic tests and treatments for inherited immune disorders.
What could go wrong
This is an observational study, not a treatment trial. It may not directly result in new therapies, and findings may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States