New pill to fight poisoning passes first safety check in humans
NCT ID NCT05628961
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested single doses of HOPO 14-1 in 42 healthy adults to see if it is safe and how the body handles it. HOPO 14-1 is designed to bind and remove toxic metals like uranium or plutonium. The trial was completed, but results are not yet available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HOPO 14-1 (a drug designed to remove toxic metals from the body)
- What this could lead to
- If successful, this could lead to a treatment for heavy metal poisoning.
- What could go wrong
- This is a very early Phase 1 study in healthy people, not patients. It only tests safety and how the drug moves through the body, not whether it works for poisoning. Side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
SRI International Clinical Trials Unit
Plymouth, Michigan, 48170, United States