New pill to fight poisoning passes first safety check in humans
NCT ID NCT05628961
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested single doses of HOPO 14-1 in 42 healthy adults to see if it is safe and how the body handles it. HOPO 14-1 is designed to bind and remove toxic metals like uranium or plutonium. The trial was completed, but results are not yet available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HOPO 14-1 (a drug designed to remove toxic metals from the body)
What this could lead to
If successful, this could lead to a treatment for heavy metal poisoning.
What could go wrong
This is a very early Phase 1 study in healthy people, not patients. It only tests safety and how the drug moves through the body, not whether it works for poisoning. Side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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SRI International Clinical Trials Unit
Plymouth, Michigan, 48170, United States