New pill boosts platelets in hard-to-treat ITP patients
NCT ID NCT05029635
First seen May 05, 2026 · Last updated May 09, 2026 · Updated 1 time
Summary
This study tested an experimental drug called HMPL-523 (sovleplenib) in 272 adults with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding risks. Participants had failed at least one prior treatment. The goal was to see if the drug could safely raise platelet counts to a safer level over 24 weeks. Results showed a meaningful improvement in durable platelet response compared to placebo.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Affiliated Hospital of North China University of Technology
Tangshan, Hebei, China
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Beijing Chaoyang Hospital of Capital Medical University
Beijing, Beijing Municipality, China
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Blood Institute of the Chinese Academy of Medical Sciences
Tianjin, Tianjin Municipality, China
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First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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Fujian Medical University Union Hospital
Fuzhou, Fujian, China
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Guangdong General Hospital
Guangzhou, Guangdong, China
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Henan Cancer Hospital
Zhengzhou, Henan, China
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Heping Hospital Affiliated to Changzhi Medical College
Changzhi, Shanxi, China
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Jinan Central Hospital Affilated to Sandong University
Jinan, Shandong, China
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Jinshan Hospital Affiliated To Fudan University
Shanghai, Shanghai Municipality, China
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Lanzhou University Second Hospital
Lanzhou, Gansu, China
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LiaoCheng People's Hospital
Liaocheng, Shandong, China
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
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People's Hospital of Peking University
Beijing, Beijing Municipality, China
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Qinghai province people's hospital
Xining, Qinghai, China
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China
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Shanxi Provincial People's Hospital
Xi’an, Shanxi, China
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Shengjing Hospital of China Medical University
Shenyang, Liaoning, China
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Southern Hospital of Southern Medical University
Guangzhou, Guangdong, China
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The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
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The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University
Huai'an, Nanjing Province, China
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The First Affiliated Hospital Of GuangXi Medical University
Nanning, Guangxi, China
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The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
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The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
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The First Affiliated hospital of USTC
Hefei, Anhui, China
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The First Affilicated Hospital of Xinjiang Medical University
Ürümqi, The Xinjiang Uygur Autonomous Region, China
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The First Hospital of Hebei Medical University
Shijiazhuang, Hebei, China
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The Second People's Hospital Of Shenzhen
Shenzhen, Guangdong, China
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, China
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The second Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, China
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The second hospital of Shanxi Medical University
Taiyuan, Shanxi, China
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Union Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
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West China Hospital，Sichuan University
Chengdu, Sichuan, China
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Xiangya Hospital Central South University
Changsha, Hunan, China
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Xiangyang Central Hospital
Xiangyang, Hubei, China
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Zhejiang Provincial Hospital of Chinese Medicine
Hangzhou, Zejiang Province, China
Conditions
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