New hope for Hard-to-Treat cancers: first human trial launches

NCT ID NCT06956690

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 25 times

Summary

This study tests a new drug, HMBD-501, in people with advanced cancers (melanoma, lung, or breast) that have stopped responding to standard treatments. The goal is to find a safe dose and see if it can shrink tumors. About 180 adults will take part in two phases: first to check safety, then to measure effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    La Jolla, California, 92093, United States

    Contact Email: •••••@•••••

  • Research Site

    RECRUITING

    Indianapolis, Indiana, 46250, United States

    Contact Email: •••••@•••••

  • Research Site

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

    Contact Email: •••••@•••••

  • Research Site

    RECRUITING

    Dallas, Texas, 75230, United States

    Contact Email: •••••@•••••

  • Research Site

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

  • Research Site

    WITHDRAWN

    Campbelltown, New South Wales, 2560, Australia

  • Research Site

    WITHDRAWN

    Miranda, New South Wales, 2228, Australia

Conditions

Explore the condition pages connected to this study.