New drug HM15211 shows promise in reversing liver damage in NASH patients

NCT ID NCT04505436

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests a new drug called HM15211 in 215 adults with NASH, a liver condition that can lead to scarring. Participants receive either the drug or a placebo for 12 months. The main goal is to see if the drug can reduce liver inflammation and scarring without making it worse.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499, South Korea

  • American Research Corporation at the Texas Liver Institute

    San Antonio, Texas, 78215, United States

  • Baylor College of Medicine - Advanced Liver Therapies

    Houston, Texas, 77030, United States

  • Bon Secours Liver Institute of Virginia - Newport News

    Newport News, Virginia, 23602, United States

  • Brigham and Women's hospital

    Boston, Massachusetts, 02115, United States

  • Carolinas Center for Liver Disease, Carolinas HealthCare System/Atrium Health

    Charlotte, North Carolina, 28204, United States

  • Centex Studies, Inc.

    Houston, Texas, 77058, United States

  • ClinSearch

    Chattanooga, Tennessee, 37421, United States

  • Consultants for Clinical Research

    Liberty Township, Ohio, 45044, United States

  • Dallas Diabetes and Endocrine Center

    Dallas, Texas, 75230, United States

  • Digestive Health Associates of Texas, P.A. (DHAT)

    Garland, Texas, 75044, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710-4000, United States

  • EWHA Womans University Mokdong Hospital

    Seoul, Seoul, 07985, South Korea

  • Eunpyeong St. Mary Hospital

    Seoul, 03312, South Korea

  • Floridian Clinical Research, LLC

    Miami Lakes, Florida, 33016, United States

  • Fresno Clinical Research Center

    Fresno, California, 93720, United States

  • Gastroenterology Health Partners, PLLC - Southern Indiana

    New Albany, Indiana, 47150, United States

  • Hanyang University Seoul Hospital

    Seoul, 04763, South Korea

  • Henry Ford Hospital

    Detroit, Michigan, 48202-2608, United States

  • Kansas Medical Clinic PA (KMC) - Gastrointestinal Medical Plaza

    Topeka, Kansas, 66606-1707, United States

  • Korea University Ansan Hospital

    Ansan, Gyeonggi-do, 15355, South Korea

  • Korea University Guro Hospital

    Seoul, Seoul, 08308, South Korea

  • Liver Center of Texas, PLLC

    Dallas, Texas, 75234, United States

  • Liver Institute Northwest

    Seattle, Washington, 98105, United States

  • Lucas Research

    Morehead City, North Carolina, 28557, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Mercy Medical Center - The Institute for Digestive Health and Liver Disease

    Baltimore, Maryland, 21202-2102, United States

  • NAFLD Research Center - Altman Clinical and Translational Research Institute

    La Jolla, California, 92037, United States

  • Natinal health insurance service Ilsan hospital

    Goyang-si, Gyeonggi-do, 10444, South Korea

  • Nevada Family Care & Wellness Center

    Henderson, Nevada, 89052, United States

  • North Alabama GI Research Center

    Huntsville, Alabama, 35801, United States

  • Ocala GI Research

    Ocala, Florida, 34471, United States

  • Pioneer Research Solutions Inc

    Houston, Texas, 77099-4307, United States

  • Precision Research Institute, LLC. (PRI)

    Chula Vista, California, 91910, United States

  • SMG-SNU Boramae Medical Center

    Seoul, Seoul, 07061, South Korea

  • San Marcus Research Clinic

    Miami Lakes, Florida, 330145602, United States

  • Schiff Center for Liver Diseases - University of Miami Leonard M. Miller School of Medicine(UMMSM)

    Miami, Florida, 33136, United States

  • Seoul National University College of Medicine - Liver Research Institute

    Seoul, Seoul, 03080, South Korea

  • Severance Hospital

    Seoul, Seoul, 03722, South Korea

  • Soonchunhyang university bucheon hospital

    Bucheon-si, Gyeonggi-do, 14584, South Korea

  • Synexus Clinical Research US, Inc

    Chicago, Illinois, 60602, United States

  • Synexus Clinical Research US, Inc

    Dallas, Texas, 75234, United States

  • Synexus Clinical Research US, Inc. - Orlando

    Orlando, Florida, 32806, United States

  • Synexus Clinical Research US, Inc. - The Villages

    The Villages, Florida, 32162, United States

  • Synexus US - Chandler

    Chandler, Arizona, 85224, United States

  • Tandem Clinical Research, LLC

    Marrero, Louisiana, 70072, United States

  • Tandem Clinical Research, LLC

    New York, New York, 10033, United States

  • Texas Clinical Research Institute, LLC

    Arlington, Texas, 76012, United States

  • Texas Liver Institute (TLI) - Texas Metabolic Center

    Austin, Texas, 78757-7571, United States

  • The Catholic University of Korea, St. Vincent Hospital

    Suwon, Gyeonggi-do, 16247, South Korea

  • The Liver Institute at Methodist Dallas

    Dallas, Texas, 75203, United States

  • UC Davis Health System - Midtown Ambulatory Care Center

    Sacramento, California, 95816, United States

  • UNC Health Care System

    Chapel Hill, North Carolina, 27514, United States

  • University of Florida College of Medicine

    Gainesville, Florida, 32610, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • University of Pittsburgh Medical Center (UPMC) - The Center for Liver Diseases

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Utah Health Care - UUHC - Kidney & Liver Clinic

    Salt Lake City, Utah, 84132, United States

  • University of Washington (UW) - Harborview Medical Center (HMC) - Hepatitis and Liver Clinic

    Seattle, Washington, 98104, United States

  • Virginia Commonwealth University (VCU) Medical Center

    Richmond, Virginia, 23298, United States

  • West Michigan Clinical Research Center

    Wyoming, Michigan, 49519, United States

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