Could a weekly pill replace daily HIV meds?
NCT ID NCT04564547
First seen Jan 27, 2026 · Last updated May 16, 2026 · Updated 16 times
Summary
This study tested whether adults with HIV-1 whose virus is already under control could safely switch from a daily pill to a once-weekly combination of two experimental drugs (islatravir and MK-8507). 161 participants took part. The main goal was to check for side effects and see how well the weekly regimen was tolerated. This is not a cure, but a step toward a more convenient treatment option.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Hotel Dieu Nantes ( Site 2310)
Nantes, Loire-Atlantique, 44093, France
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CHU de Toulouse - Hopital Purpan ( Site 2302)
Toulouse, Haute-Garonne, 31059, France
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CHUV (centre hospitalier universitaire vaudois) ( Site 2605)
Lausanne, Canton of Vaud, 1011, Switzerland
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Centre Hospitalier Regional du Orleans ( Site 2304)
Orléans, Loiret, 45100, France
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Chatham County Health Department ( Site 2707)
Savannah, Georgia, 31410, United States
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DCOL Center for Clinical Research ( Site 2715)
Longview, Texas, 75605, United States
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Hopital Avicenne ( Site 2305)
Bobigny, Seine-Saint-Denis, 93000, France
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Hopital Gui de Chauliac. ( Site 2303)
Montpellier, Herault, 34295, France
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Hopital Saint Louis ( Site 2308)
Paris, 75010, France
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Hopital Saint-Antoine ( Site 2307)
Paris, 75012, France
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Hopitaux Universitaires de Geneve HUG ( Site 2604)
Geneva, Canton of Geneva, 1211, Switzerland
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Infectious Disease Specialists Of Atlanta PC ( Site 2704)
Decatur, Georgia, 30033, United States
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Inselspital Universitaetsspital Bern ( Site 2603)
Bern, Canton of Bern, 3010, Switzerland
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Kansas City CARE Clinic ( Site 2703)
Kansas City, Missouri, 64111, United States
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Men's Health Foundation ( Site 2710)
Los Angeles, California, 90069, United States
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Midway Immunology and Research ( Site 2713)
Ft. Pierce, Florida, 34982, United States
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Pitie Salpetriere University Hospital-Infectious Disease - Tropical Diseases ( Site 2306)
Paris, Île-de-France Region, 75013, France
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Pueblo Family Physicians ( Site 2702)
Phoenix, Arizona, 85015, United States
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Saint Hope Foundation, Inc. ( Site 2716)
Bellaire, Texas, 77401, United States
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Texas Centers for Infectious Disease Associates P.A. ( Site 2709)
Fort Worth, Texas, 76104, United States
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Triple O Research Institute, P.A. ( Site 2712)
West Palm Beach, Florida, 33407, United States
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Universitaetsspital Basel ( Site 2602)
Basel, Canton of Basel-City, 4031, Switzerland
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Universitaetsspital Zuerich ( Site 2601)
Zuerich, Canton of Aargau, 8091, Switzerland
Conditions
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