New HIV vaccine combo enters human safety trials
NCT ID NCT06205056
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a new HIV vaccine combination is safe and can trigger an immune response. About 78 healthy adults will receive either the vaccine or a placebo. The study uses two different dosing schedules to see which works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HIV vaccine combination (Ad26.Mos4.HIV and CH505 TF chTrimer + ALFQ)
What this could lead to
If successful, this could help develop a vaccine that trains the immune system to fight HIV.
What could go wrong
This is an early Phase 1 trial focused on safety, not effectiveness. The vaccine may not produce a strong immune response or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Makerere University Walter Reed Project (MUWRP)
RECRUITINGKampala, Uganda
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••